Bus Route 3 travels from the Strawberry Mansion to the Frankford Transportation Center via Cecil B. Moore Blvd, with stops at Kensington and Allegheny Aves, Front and Dauphin Sts, Broad and Cecil B. Moore, 20th and Cecil B. More, and 33rd and Cecil B. More.

Bus Route 5 runs from Center City to the Frankford Transportation Center via Frankford Ave, stopping at Frankford and Torresdale, Lehigh, Girard, and Market Streets.
 
Bus Route 8 operates from Olney Transportation Center to the Frankford Transportation Center via Roosevelt Boulevard and Tabor Road, making stops at Tower and Roosevelt Blvds, Fisher and Rising Sun Aves, and 5th and Tabor Road. This Route only operates on Weekdays.
 
Bus Route 14 travels between Oxford Valley Mall and Frankford Transportation Center, with stops at or near Sesame Place, IRS, Langhorne Station (R3), Red Lion Shopping Area, Pennypack Park, Nazareth Hospital, Roosevelt Mall and Frankford Hospital.

Bus Route 19 runs from Krewstown and Torresdale Station to the Frankford Transportation Center via Algon Avenue, stopping at Oxford and Summerdale Aves, Whitaker and Cottman Aves, Krewstown Rd and Gregg St, Willits and Aston Rds, and Torresdale Station at Grant Ave and James St (R7).
 
Bus Route 20 operates between Frankford Transportation Center and Franklin Mills through Frankford, Academy Gardens, and Parkwood Manor, making stops at or near Roosevelt Mall, and Nazareth Hospital.
 
Bus Route 26 runs from Germantown to Olney and the Frankford Transportation Center via Tabor Road, making stops at Bridge St and Torresdale Ave, Tabor Rd and Levick St, Rising Sun and Olney Aves, Chew and Chelten Aves, and Chelten Ave east of Morris St.
 
Bus Route 58 operates between Frankford Transportation Center and Neshaminy Mall with stops at Neshaminy Falls and Somerton Stations (R3), Bucks County, Leo and Roosevelt Malls.
 
Bus Route 59 travels from Bells Corner to Arrott Terminal via Castor Avenue, stopping at Arrot St Terminal, Levick St, Cottman Ave, and Bustleton Ave (Bell¬s Corner).
 
Bus Route 66 operates from Torresdale to the Frankford Transportation Center via Frankford Ave, stopping at Cottman Ave, Rhawn St, Gregg St, and City Line Ave.
 
Bus Route 67 travels between Franklin Mills and Frankford Transportation Center with stops in Lawndale, Fox Chase, and Northeast Philadelphia, including Academy and Boulevard Plazas, and Knights Road Shopping Center.
 
Bus Route 73 travels from Port Richmond to the Frankford Transportation Center via Bridge and Richmond Streets, making stops at the Frankford Transportation Center, Bridge and Thompson Sts, Richmond and Westmoreland Sts.
 
Bus Route 75 runs from Nicetown to Arrott Terminal via Wyoming Ave, stopping at Arrott St Terminal, Wyoming Circle, 5th and Wyoming, Broad and Wyoming, and Wayne and Windrim Aves.
 
Bus Route 88 services Pennypack Woods or Holy Redeemer Hospital stopping at the Frankford Transportation Center, Holme Circle, Bethayres Station, (R3) and Holy Redeemer Hospital.
 
Bus Route 89 operates from Kensington to Frankford via Juniata Park and Port Richmond, with stops at Arrott St Terminal, Kensington and Allegheny Aves, York St and Aramingo Ave, and Front St and Susquehanna Ave.
 
Bus Route J travels from Bridesburg to Germantown via Frankford and Logan, stopping at Richmond and Orthodox Sts, 5th and Lindley Ave, Broad and Lindley Ave, and Wissahickon and Chelten Aves.
 
Bus Route K runs from East Falls to Arrott Terminal via Germantown, making stops at Arrott St Terminal, 2nd and Godfrey Ave, 66th and Broad, Chelten and Wayne Aves, and Ridge and Midvale Aves.
 
Bus Route R operates from the Wissahickon Transportation Center to the Frankford Transportation Center via Roosevelt Blvd and Hunting Park Ave, making stops at the Frankford Transportation Center, Roosevelt and Tower Blvds, Roosevelt and 5th, Fox St and Hunting Park Ave, 29th and Allegheny Ave, and the Wissahickon Transportation Center.

Market-Frankford Line runs service from 69th Street Terminal to the Frankford Transportation Center, stopping at a variety of locations along Market Street and Frankford Ave.